Cannabis has historically been associated with stigma due to its effects, but it is now receiving increasing acknowledgment for its potential in various medical fields. Recent years have witnessed a significant rise in research focused on the therapeutic properties of cannabis, especially regarding its advantages for neurological conditions.
Beyond its well-known applications for stress relief, alleviating depression, and enhancing sleep quality, cannabis shows promise in addressing a range of neurological disorders. This article explores five such conditions and investigates how a BudExpressNow Canada cannabis product like cannabis plays a role in their therapeutic applications.
Table of Contents
Key Takeaways:
- Certain cannabinoids and terpenes demonstrate unique effects on various neurological disorders.
- Linalool, myrcene, and limonene possess anti-convulsant properties.
- Equal concentrations of THC and CBD, alongside other cannabis compounds, may hold potential in cancer treatment.
A Natural Approach to Managing Neurological Disorders
The approach to addressing the complexities of conditions such as Alzheimer’s disease (AD), brain tumors, Parkinson’s disease (PD), intractable epilepsy, and chronic traumatic encephalopathy (CTE) varies according to individual patient needs and the severity of their conditions.
Cannabis is a Viable Treatment Option
Epilepsy
The endocannabinoid system plays a role in influencing the seizure threshold. THC can completely halt seizures, in contrast to phenobarbital and diphenylhydantoin. Animal studies have indicated acute spikes in endocannabinoid production alongside a sustained increase in CB1 production over time. Researchers have recognized the anti-convulsant properties of cannabinoids even at levels below sedation.
THC, THCA, and linalool, a terpenoid found in cannabis, have been subjects of scientific investigation. The discourse around THCA is intricate, with discussions about its CB1 activity versus its spontaneous conversion to THC.
Recent findings have also illuminated the anti-convulsant properties of cannabidiolic acid (CBDA), suggesting its serotonergic effects. CBDA demonstrates a significantly higher affinity for the 5-HT1A receptor compared to CBD.
If you are interested in exploring cannabis vape pens to assist with your condition, look for products that contain THC, CBD, THCA, or Linalool.
OneStop – THC Distillate Disposable Vape Pen Skittlez features linalool as a primary terpene with THC ranging from 16 to 21%.
Brain Tumors
Numerous studies have investigated the use of cannabis in patients diagnosed with brain tumors. A study published in the British Journal of Cancer in 2006 found that administering THC directly into tumors in patients with glioblastoma multiforme (GBM) marginally extended their lifespans beyond expectations in nine human cases.
Additionally, a case report from the Journal of Child’s Nervous System documented complete regression of residual tumors in two children with pilocytic astrocytomas following cannabis use.
THCA, as a peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, surpasses CBDA, CBD, or THC in potential impact. PPARs function as ligand-binding transcription factors, offering the promise to selectively target cancer cells while sparing normal cells. The synergistic effects of THCA with other cytotoxic agents underscore its potential in cancer therapy.
Equal concentrations of THC and CBD, when combined with THCA, CBDA, and cytotoxic terpenoids like limonene, show significant potential in cancer treatment, as indicated by a study in the Planta Medicine Journal. Disposable cannabis pens can house these cannabinoids and terpenes in a single cartridge.
Parkinson’s Disease
An observational study revealed that 22 out of 28 patients could tolerate smoked cannabis, presumably THC-predominant. The study also highlighted acute benefits, including improvements in tremor, rigidity, and bradykinesia among participants.
In Parkinson’s disease, cell loss in the substantia nigra leads to widespread pathology over time. Tau proteins, which maintain the cytoskeleton and assist with axonal transport in neurons, undergo modifications that result in the formation of neurofibrillary tangles.
Nabiximols, a cannabis-based oral spray, significantly reduced tangles when administered to parkin-null mice expressing human tau. This treatment improved dopamine metabolism and glial function while mitigating oxidative stress levels.
THC vape pens like BudExpressNow Canada cannabis can be an excellent choice if you aim to reduce tremors.
Alzheimer’s Disease
Alzheimer’s disease (AD) involves the formation of senile plaques from β-amyloid (Aβ) proteins, which arise when enzymes cleave a precursor protein (APP). It also encompasses the accumulation of neurofibrillary tangles from tau proteins with excessive phosphate groups attached. At times, these tangles may appear prior to the β-amyloid plaques. Once these processes commence, the progression of the disease becomes inexorable.
CBD acts as a protective antioxidant for the brain, safely interacting with NMDA receptors. It combats Alzheimer’s disease by halting Aβ plaque formation, reducing harmful ROS production, and preventing damage to lipids in PC12 cells exposed to Aβ. CBD also obstructs tau proteins from acquiring excessive phosphate groups on PC12 neurons impacted by Aβ.
A study involving patients receiving THC-predominant (2.5–30 mg/dose), CBD-predominant, and THCA—mainly administered through tinctures and confections—demonstrated reduced dependency on neuroleptic medications, lessened agitation, improved appetite, managed aggression, enhanced sleep quality, elevated mood, decreased demands for nursing care, mitigated self-harming tendencies, and controlled pain.
The components of cannabis exhibit potential to alleviate various symptoms associated with this complex disorder:
- Agitation may find relief with THC, CBD, and linalool.
- Psychosis symptoms might benefit from CBD.
- THC and linalool may help alleviate insomnia and restlessness.
- THC is indicated for anorexia, while THC, CBD, and linalool may assist with aggression.
- THC, limonene, and CBD could potentially aid in managing depression.
- THC and CBD are recognized for their pain-relieving properties.
- Alpha-pinene, combined with THC, is associated with memory enhancement.
- CBD and THC are linked to neuroprotection, while THC, CBD, and THCA could contribute to reduced Aβ plaque formation.
Traumatic Brain Injury / Chronic Traumatic Encephalopathy
Cannabis, especially chemovars that combine THC and CBD, can alleviate symptoms associated with CTE, including headaches, nausea, insomnia, dizziness, agitation, substance abuse, and psychotic symptoms.
A 2019 study indicated that varying concentrations of THC and CBD help alleviate stress, agitation, depression, and anxiety—common emotional responses in cases of chronic traumatic encephalopathy. Cannabinoids aid in reducing glutamate excitotoxicity, a process that causes nerve cell damage following a traumatic brain injury.
Want to Use Cannabis for Your Current Condition?
Engaging in cannabis use has become a common method to capitalize on its benefits. If you’re looking to avoid potential health risks associated with traditional methods, cannabis vapes present a feasible alternative.
cannabis have a heating chamber or element that vaporizes the flower or concentrate. Online cannabis stores offer numerous options to help you find the best vape pen for your requirements. You can select based on the pen type, including disposable vape pens, whether you prefer Sativa-dominant or Indica-dominant cartridges with high THC or specific concentrates.
Weed Vape Pens Treat Your Condition
Neurological treatment for the conditions discussed in this article requires considerable advancement. However, emerging methods such as utilizing cannabis, including through a cannabis pen, in treatment protocols demonstrate promise. Research studies and anecdotal evidence suggest that cannabis, with its varying levels of THC, CBD, and other compounds, can interact with the ECS to aid in managing symptoms of these conditions.
Frequently Asked Questions
Can a dab pen provide the same experience as a vape pen?
A dab pen and a vape pen both vaporize cannabis concentrates, but they differ in intensity and usage. Dab pens are designed for solid concentrates like wax and produce a more potent effect. Vape pens utilize liquid concentrates, offering a milder, more controlled experience.
Are THC pens cheap?
The average cost of a cannabis pen is around $50. You can find options as affordable as $20, while others can exceed $200. The price variation is influenced by battery life and the array of features available.
Can my current medication interact with the active ingredient in my cannabis vape?
This will depend on your prescription medication. If you take antidepressants while managing Parkinson’s disease, cannabis may lead to an initial increase in serotonin, intensifying the body’s reliance on these substances, potentially worsening depression and anxiety over time. It is advisable to consult your doctor before considering the addition of cannabis to your current medication regimen.
Are cannabis pens the best alternative when treating health issues with cannabis?
Weed pens provide a cleaner way to consume cannabis without the smoke from combustion. This has made them a popular choice for individuals seeking a less harmful and more discreet option to assist with health issues like pain and anxiety.
However, whether cannabis pens are the best choice can depend on the individual user. As we continue to learn about their long-term effects, it is essential for anyone considering their use for health reasons to consult with a doctor first. This ensures the selection of the most suitable method for their health needs.
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